1602, England. Her majesty's premier spy, Sir Nicholas Fury, fends off an assassination attempt on the Queen by winged warriors rumored to be in service to a mad despot named Doom. News is spreading of "witchbreed" sightings and at the center of the rising chaos is Virginia Dare, a young girl newly arrived from the New World, guarded by a towering Indian warrior. Can Fury and his allies find a connection to these unusual happenings before the whole world ends?