When a crown is stolen from the Crystal Empire, Twilight Sparkle pursues the thief into an alternate world where she transforms into a teenage girl who must survive her biggest challenge yet, high school. With help from her new friends who remind her of Ponyville's Applejack, Rarity, Rainbow Dash, Pinkie Pie, and Fluttershy, she embarks upon a quest to find the crown and change the destiny of these two parallel worlds.