Using data siphoned off the U.S. intelligence agencies' threat matrix, information not related to terrorism, but rather violent crimes of a personal nature, during each episode, the former CIA agent and his enigmatic partner identify a 'person of interest' and set about solving the mystery of the impending crime. Tapping into the world's Big Brother-like surveillance network, the shadowy duo knows that something bad is going to happen; it's their mission to discover what that event will be.