Dr. Jake Rosen, renowned pathologist, deputy chief medical examiner, and seasoned New Yorker, teams up again with his unlikely partner, crusading civil rights attorney and shopaholic Manny Manfreda, to solve a string of gruesome attacks plaguing the city. "The Vampire" stalks his victims, sedates them, and then absconds with vials of their blood. The mystery deepens when DNA analysis suggests links to the crimes and tragedies of another time and another nation.