Desperate to start a family, New York schoolteacher, April Epner hits a midlife crisis when, in quick succession, her husband unexpectedly abandones her and her adoptive mother dies. She gets another shock when she meets her biological mother, an eccentric, self-centered talk show host, whom at first she rejects. Then the divorced dad of one of her students begins courting April. As her life is turned upside-down, April finds herself opening up in ways she had never imagined.