Maggie runs a group that dubs voices for movies. She spends much of her time fending off her three pushy daughters, and gets her kicks with her far older Sicilian lover. Connie, on the other hand, has a taste for younger men. These two best friends are getting past their prime, which is why they plan to have one last great adventure. But on the road from Texas to California and back, the women get caught up in events beyond their control. Packing a .38 Special, they blaze their trail across the Southwest, bumping into one zany character after another.