An ingenious serial murderer is targeting San Francisco's newlywed couples on their wedding nights. The murderer will kill the groom before the bride and then remove both wedding rings. Assigned to track down this maniac is homicide inspector Lindsay Boxer, who, seems more than prepared for the biggest challenge of her career. But what Lindsay is not prepared for is facing her own mortality. She has been diagnosed with a blood disease that nearly always proves fatal and may she not live long enough to bring the honeymoon killer to justice.