Cover image for The hope, hype & reality of genetic engineering : remarkable stories from agriculture, industry, medicine, and the environment
The hope, hype & reality of genetic engineering : remarkable stories from agriculture, industry, medicine, and the environment
Avise, John C.
Personal Author:
Publication Information:
Oxford ; New York : Oxford University Press, 2004.
Physical Description:
xiii, 242 pages : illustrations ; 24 cm
Reading Level:
1500 Lexile.
Format :


Call Number
Material Type
Home Location
Item Holds
QH442 .A98 2004 Adult Non-Fiction Non-Fiction Area

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An introductory tour into the stranger-than-fiction world of genetic engineering, a scientific realm inhabited by eager researchers intent upon fashioning a prodigious medley of genetically modified (GM) organisms to serve human needs.

Author Notes

John C. Avise, Ph.D., is Professor of Genetics at the University of Georgia

Reviews 1

Choice Review

For the past quarter century, genetic engineering has accomplished remarkable transformations. This technology has modified genomes, designed vectors to transmit desired traits, cloned identical creatures, transformed organisms, and combined traits from separate species to form transgenic stock. Some of these technological developments are in practical use, such as in the manufacture of humulin, the growth of plants with herbicides, and vaccine production; others remain to be proved effective and useful. With seven sections, divided into fascinatingly readable and lucid chapters, the book examines the advancement of genetic engineering into the realms of industry, agriculture, animal manipulation, environmental affairs, and, of course, the realm of humans. With the latter, Avise (Univ. of Georgia) explains the potential of stem cells, clones, and genetic therapies and examines the hazards. Each section describes individual instances of genetic modification, from microbes to plants to animals, and how this technology of ongoing or contemplated manipulation might impact society. The author appraises each of the 60 compiled projects for their worthiness under current circumstances and also with regard to potential undetected complications. This is an exciting exploration into the new and unknown world of genetic manipulation, where restraint is cautioned. ^BSumming Up: Recommended. All levels. R. A. Hoots Woodland Community College

Table of Contents

1 A Tale of Good and a Tale of Evilp. 3
A New Papayap. 4
Microbiological Terrorismp. 5
2 Framework of an Unfolding Revolutionp. 9
The Purview of Genetic Engineeringp. 10
Preliminary Genetic Backgroundp. 11
3 Engineering Microbesp. 16
Insulin Factoriesp. 17
A Growth Industryp. 19
Microbial Factories for Pharmaceutical Drugsp. 21
More Industrious Microbesp. 23
Accelerated, Directed Evolutionp. 26
Concluding Thoughtsp. 28
4 Getting Creative with Cropsp. 30
Combating Corn Borersp. 34
Insecticidal Cottonp. 38
Defensins and Potato Faminesp. 41
Herbicide-Tolerant Soybeansp. 43
Herbicide-Resistant Weedsp. 46
Terminator Technologyp. 49
Chloroplast Concoctionsp. 51
Alleviating Dietary Deficiencies: The Golden Rice Storyp. 54
Supplementing Dietary Supplements: Nutrient Boostsp. 56
Going Bananas with Vaccinesp. 58
Plantibiotics and Pharmaceutical Farmingp. 61
Alleviating Allergiesp. 64
Plastics from Plantsp. 66
The Flavr Savr Tomatop. 68
A Comucopia of GM Productsp. 70
Concluding Thoughtsp. 71
5 Genetic Engineering in the Barnyardp. 77
Spider's Silk from Goat's Milkp. 78
Low Phosphorus Enviropigsp. 80
Mice as Basic Research Modelsp. 82
Hello Dollyp. 85
Cow Clonesp. 86
Barnyard Bioreactorsp. 88
Vaccinating for Animal Healthp. 91
Engineering Foods for Animalsp. 92
Cloned Organ-Donor Pigsp. 94
Possibilities with Poultryp. 96
Copy Catsp. 98
Good-bye Dollyp. 100
Concluding Thoughtsp. 102
6 Fields, Forests, and Streamsp. 103
Pulp Nonfictionp. 104
Antimalarial Mosquitoesp. 106
Fat, Sexy Salmonp. 108
Antifreeze Proteinsp. 111
Mutation-Detecting Fishp. 113
Sentinels of Aquatic Pollutionp. 115
Transgenic Environmental Biosensorsp. 117
Phytoremediation of Mercury Poisonsp. 119
Phytoremediation of Organic Pollutantsp. 122
Salt and Drought Plantsp. 124
Bioremediating Bacteriap. 126
Cries over Spilled Oilp. 128
Rabbit Contraceptionp. 130
Daughterless Carpp. 132
Pesticide Detoxificationp. 134
Blue Rose Petals and a Mauve Carnationp. 137
No-mow Lawnsp. 139
Sperm Whale Oils and Jojoba Waxesp. 141
Rescuing Endangered Speciesp. 143
Concluding Thoughtsp. 145
7 Genetic Tinkering with Humansp. 148
Gene Therapies on SCIDsp. 149
Gene Therapies in the Worksp. 151
New Angles on Gene Therapy Vectorsp. 153
Tissue Therapy via Gene Therapy: The Angiogenesis Storyp. 156
Tissue Therapy via Therapeutic Cloningp. 158
Embryonic Stem Cellsp. 160
More on Stem Cellsp. 162
Whole-Human Clonesp. 165
Engineering the Germlinep. 167
More New-Age Eugenicsp. 170
Concluding Thoughtsp. 172
Epiloguep. 175
Appendix Tools and Workshops of Genetic Engineeringp. 179
Restricted Activitiesp. 179
Cut and Pastep. 181
Copy and Duplicatep. 182
Viral Vectorsp. 184
Jumping Genesp. 187
Galls and Goals in Plant Transformationp. 188
Promoting Promoters and Constructing Constructsp. 190
Reporter Genesp. 192
Test-Tube Gene Cloningp. 194
Hybridizing DNA Moleculesp. 195
Knockouts and Resuscitationsp. 197
Glossaryp. 201
References and Further Readingp. 211
Indexp. 237