Cover image for Biomedical technology and devices handbook
Title:
Biomedical technology and devices handbook
Author:
Moore, James E., Jr., 1964-
Publication Information:
Boca Raton : CRC Press, [2004]

©2004
Physical Description:
1 volume (various pagings) : illustrations ; 26 cm.
Language:
English
Contents:
Measuring Body Temperature / Daniel S. Moran, Stephen L. Gaffin, Liran Mendel -- Ultrasonic Blood Flow and Velocity Measurement / Craig J. Hartley -- Electromagnetic Blood Flow Measurements / Reza Tabrizchi, Noriko Iida -- Electromyography: Detection, Processing, and Applications / Marco Pozzo, Dario Farina, Roberto Merletti -- Evoked Potentials / Hermann Hinrichs -- Electroencephalography / Hermann Hinrichs -- Hearing and Audiologic Assessment / Herbert Jay Gould, Daniel S. Beasley -- Magnetic Resonance Imaging / Timothy P.L. Roberts, Christopher K. Macgowan -- Ultrasonic Imaging / Elisa E. Konofagou -- Emission Imaging: SPECT and PET / Anthony J. McGoron, Juan Franquiz -- Endoscopy / Thomas D. Wang, George Triadafilopoulos -- Functional Brain Mapping Using Intracranial Source Imaging / George Zouridakis, Darshan Iyer -- Molecular Biology Techniques and Applications / Lidia Kos, Roman Joel Garcia -- Theoretical Considerations for the Efficient Design of Dna Arrays / Arnold Vainrub ... [et al.] -- Biological Assays: Cellular Level / Clark T. Hung, Robert L. Mauck -- Histology and Staining / S.E. Greenwald, A.G. Brown.

Radioimmunoassay: Technical Background / Eiji Kawasaki -- Genetic Engineering of Animals / Carl A. Pinkert -- Gene-Enhanced Tissue Engineering / Stelios T. Andreadis -- Shear Stress and Chondrocytes / C.Corey Scott, Kyriacos A. Athanasiou -- Bioactive Scaffold Design for Articular Cartilage Engineering / Eric M. Darling, Kyriacos A. Athanasiou -- Anesthesia/Monitoring Devices / Spencer Kee -- Intraoperative Neurophysiological Monitoring Carla S. Hatten, George Zouridakis -- Technical Considerations in the Contruction of Vascular Anastomoses / Mark A. Grevious ... [et al.] -- Minimally Invasive Cardiovascular Technologies / James E. Moore ... [et al.] -- Stereotactic Procedures / Michael D. Weil -- Ambulatory Applications for Monitoring Physiological Parameters / Carolyn B. Yucha, Pei-Shan Tsai, Kristine S. Calderon -- Neural Prostheses for Movement Restoration / Dejan B. Popovic -- Pharmaceutical Technical Background on Delivery Methods / Robert S. Litman ... [et al.] -- Hyperbaric Oxygen Therapy / Tonja Weed, Timothy Bill, Thomas J. Gampper -- Image-Guided Thermal Therapy / Rajiv Chopra -- Medical Robotics / Kevin Cleary, Charles C. Nguyen.
ISBN:
9780849311406
Format :
Book

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Summary

Summary

Concise yet comprehensive, the Biomedical Technology and Devices Handbook illuminates the equipment, devices, and techniques used in modern medicine to diagnose, treat, and monitor human illnesses. With topics ranging from the basic procedures like blood pressure measurement to cutting-edge imaging equipment, biological tests, and genetic engineering, this book is organized to navigate smoothly from simple procedures and concepts to the more sophisticated and complex ones. Each section contains a description of the technique, its technical considerations, and its use according to its applications and relevant body systems. The book includes references to relevant Web sites, protocols, problems, and solutions.


Table of Contents

Daniel S. Moran and Stephen L. Gaffin and Liran MendelCraig J. HartleyReza Tabrizchi and Noriko IidaMarco Pozzo and Dario Farina and Roberto MerlettiHermann HinrichsHermann HinrichsHerbert Jay Gould and Daniel S. BeasleyTimothy P.L. Roberts and Christopher K. MacgowanElisa E. KonofagouAnthony J. McGoron and Juan FranquizThomas D. Wang and George TriadafilopoulosGeorge Zouridakis and Darshan IyerLidia Kos and Roman Joel GarciaArnold Vainrub and Tong-Bin Li and Yuriy Fofanov and B. Montgomery PettittClark T. Hung and Robert L. MauckS.E. Greenwald and A.G. BrownEiji KawasakiCarl A. PinkertStelios T. AndreadisC. Corey Scott and Kyriacos A. AthanasiouEric M. Darling and Kyriacos A. AthanasiouSpencer KeeCarla S. Hutten and George ZouridakisMark A. Grevious and Francis Loth and Steven A. Jones and Nurullah Arslan and Michael A. Curi and Lewis B. Schwartz and Hisham S. BassiounyJames E. Moore, Jr. and Marc Jalisi and Michael R. Moreno and Eric CrumplerMichael D. WeilCarolyn B. Yucha and Pei-Shan Tsai and Kristine S. CalderonDejan B. PopovicRobert S. Litman and Maria de la Cova and Icel Gonzalez and Eduardo LopezTonja Weed and Timothy Bill and Thomas J. GampperRajiv ChopraKevin Cleary and Charles C. Nguyen
I Basic Clinical Measurements
1 Measuring Body Temperaturep. 1
1.1 Introductionp. 1
1.2 Noninvasive Sites for T[subscript c] Measurementsp. 4
1.3 Invasive Sites for T[subscript c] Measurementsp. 5
1.4 Methods and Instrumets for T[subscript c] Measurementp. 6
1.5 Summaryp. 9
Referencesp. 9
2 Ultrasonic Blood Flow and Velocity Measurementp. 1
2.1 Introductionp. 1
2.2 Ultrasound Physicsp. 1
2.3 Ultrasonic Transducersp. 2
2.4 Transit-Time Dimensionp. 2
2.5 Transit-Time Velocity and Flowp. 4
2.6 Doppler Velocityp. 6
2.7 Continuous Wave Dopplerp. 6
2.8 Pulsed Doppler Velocityp. 7
2.9 Doppler Signal Processingp. 8
2.10 Multigate and Color Dopplerp. 10
2.11 Feature Extractionp. 11
2.12 Converting Velocity to Volume Flowp. 12
2.13 Other Applications of Doppler Velocimetryp. 13
2.14 Artifacts and Limitationsp. 13
2.15 Summaryp. 15
Referencesp. 15
3 Electromagnetic Blood Flow Measurementsp. 1
3.1 Introductionp. 1
3.2 Methodology and Instrumentationp. 2
3.3 Discussionp. 14
Referencesp. 17
4 Electromyography: Detection, Processing, and Applicationsp. 1
4.1 Introductionp. 1
4.2 EMG Signal Generation and Detectionp. 2
4.3 EMG Signal Processingp. 36
4.4 Applications of EMG in Basic Research and Clinical Routinep. 49
4.5 Conclusionp. 60
Acknowledgmentsp. 60
Referencesp. 60
5 Evoked Potentialsp. 1
5.1 Basic Operational Mechanismsp. 1
5.2 Signal Processingp. 6
5.3 Detecting of Malfunctionsp. 15
Referencesp. 17
Additional Recommendations and Standardsp. 17
6 Electroencephalographyp. 1
6.1 Basic Operational Mechanismsp. 1
6.2 Signal Processingp. 6
6.3 Detecting Malfunctionsp. 18
Referencesp. 20
Additional Recommendations, Standards, and Further Readingp. 20
7 Hearing and Audiologic Assessmentp. 1
7.1 Structure of the Auditory Systemp. 2
7.2 Sound and the Decibelp. 9
7.3 Assessing the Auditory Systemp. 11
7.4 Degree of Lossp. 15
7.5 Speech Reception Thresholdp. 15
7.6 Speech Recognition Testingp. 16
7.7 Otoacoustic Emissionsp. 17
7.8 Spontaneous Otoacoustic Emissions (SOAE)p. 17
7.9 Transient-Evoked Otoacoustic Emissionsp. 17
7.10 Distortion Product Otoacoustic Emissionsp. 19
7.11 Stimulus Frequency Otoacoustic Emissionsp. 20
7.12 Immittance Audiometryp. 20
7.13 Acoustic Reflexp. 22
7.14 Common Pathologic Conditions of the Auditory Systemp. 23
7.15 Sensory-Neural Lossp. 25
7.16 Central Disordersp. 27
7.17 Amplificationp. 27
Referencesp. 28
II Imaging Techniques
8 Magnetic Resonance Imagingp. 1
8.1 Introductionp. 1
8.2 Hardware Components of an MRI Scannerp. 2
8.3 Image Encodingp. 3
8.4 Endogenous Tissue Contrastp. 5
8.5 Contrast Agentsp. 10
8.6 fMRIp. 13
8.7 Magnetic Resonance Angiography and Flow Quantificationp. 14
8.8 MR Spectroscopy (MRS) and Spectroscopic Imaging (MRSI)p. 23
8.9 MR Evaluation of Cardiac Function: An Example of an Integrated MRI Examp. 24
8.10 Conclusionp. 26
Suggested Further Readingp. 27
9 Ultrasonic Imagingp. 1
9.1 Fundamentals of Ultrasoundp. 1
9.2 Transducersp. 7
9.3 Ultrasound Fieldsp. 10
9.4 Ultrasonic Imagingp. 16
9.5 Current Developmentsp. 23
Referencesp. 30
10 Emission Imaging: SPECT and PETp. 1
10.1 Introductionp. 1
10.2 Radioisotopesp. 2
10.3 Radiopharmaceuticalsp. 8
10.4 Instrumentation for Emission Imagingp. 28
Acknowledgmentp. 46
Referencesp. 46
11 Endoscopyp. 1
11.1 Introductionp. 1
11.2 Basic Components of an Endoscopep. 2
11.3 Endoscopic Imagingp. 5
11.4 Endoscopic Image Formationp. 8
11.5 Endoscopic Image Resolutionp. 11
11.6 Endoscopic Image Signal-to-Noise Ratiop. 12
11.7 Color Image Processingp. 13
11.8 Endoscopic Retrograde Cholangiopancreatographyp. 15
11.9 Endoscopic Ultrasoundp. 16
11.10 Optical Coherence Tomographyp. 17
11.11 High Magnification Endoscopyp. 19
11.12 Chromoendoscopyp. 20
11.13 Fluorescence Imagingp. 20
11.14 Wireless Capsulep. 23
11.15 Virtual Endoscopyp. 24
11.16 Summary and Conclusionsp. 25
Referencesp. 26
12 Functional Brain Mapping Using Intracranial Source Imagingp. 1
12.1 Introductionp. 1
12.2 Neurophysiological Signalsp. 2
12.3 Mathematical Modelingp. 3
12.4 Neurophysiological Recordingsp. 5
12.5 Data Analysisp. 8
12.6 Application Examplesp. 10
12.7 Concluding Remarksp. 13
Referencesp. 15
III Biological Assays
13 Molecular Biology Techniques and Applicationsp. 1
13.1 Introductionp. 1
13.2 Isolation of Nucleic Acidsp. 2
13.3 Analysis of Nucleic Acidp. 3
13.4 Applicationsp. 10
Acknowledgmentsp. 18
Referencesp. 19
14 Theoretical Considerations for the Efficient Design of DNA Arraysp. 1
14.1 Introductionp. 1
14.2 Surface Designp. 1
14.3 DNA Biosensorsp. 6
14.4 Conclusionsp. 12
Acknowledgmentsp. 12
Referencesp. 12
15 Biological Assays: Cellular Levelp. 1
15.1 Introductionp. 1
15.2 Cell Culturep. 1
15.3 General Microscopy Principlesp. 9
15.4 Flow Cytometryp. 15
15.5 Molecular Biologyp. 18
15.6 Conclusionsp. 27
Acknowledgmentsp. 27
Referencesp. 28
16 Histology and Stainingp. 1
16.1 Introductionp. 1
16.2 Fixationp. 3
16.3 Tissue Processingp. 5
16.4 Cuttingp. 7
16.5 Stainingp. 10
16.6 Mountingp. 17
16.7 Microscopyp. 18
Referencesp. 21
17 Radioimmunoassay: Technical Backgroundp. 1
17.1 Introductionp. 1
17.2 Principlep. 1
17.3 Radioimmunoassay Techniquesp. 3
17.4 Validation of a Radioimmunoassay Procedurep. 6
17.5 Applicationsp. 7
Referencesp. 9
IV Genetic and Tissue Engineering
18 Genetic Engineering of Animalsp. 1
18.1 Introductionp. 1
18.2 Production of Transgenic Animalsp. 4
18.3 Evolving Technologiesp. 8
18.4 Conclusions and Future Directionsp. 9
Acknowledgmentsp. 10
Referencesp. 10
19 Gene-Enhanced Tissue Engineeringp. 1
19.1 Introductionp. 1
19.2 Gene Therapeuticsp. 2
19.3 Genetic Modification for Tissue Engineeringp. 7
19.4 Challenges Facing Gene Deliveryp. 12
19.5 Summaryp. 16
Referencesp. 17
20 Shear Stress and Chondrocytesp. 1
20.1 Introductionp. 1
20.2 Chondrocytes and Cell Adhesionp. 2
20.3 Mechanical Property Measurement of Single Cellsp. 6
20.4 Effect of Shear Stress on Chondrocytesp. 8
20.5 Conclusionsp. 12
Acknowledgmentsp. 13
Referencesp. 13
21 Bioactive Scaffold Design for Articular Cartilage Engineeringp. 1
21.1 Introductionp. 1
21.2 Scaffold Materialsp. 2
21.3 Surface Modificationp. 8
21.4 Growth Factor Inclusionp. 11
21.5 Conclusionp. 11
Acknowledgmentp. 12
Referencesp. 12
V Interventional Disease Treatment
22 Anesthesia/Monitoring Devicesp. 1
22.1 Technical Backgroundp. 1
22.2 Signal Processingp. 8
Referencesp. 8
23 Intraoperative Neurophysiological Monitoringp. 1
23.1 Introductionp. 1
23.2 Overviewp. 1
23.3 Neurophysiological Recordings: Spontaneous Activityp. 4
23.4 Neurophysiological Recordings: Evoked Potentialsp. 6
23.5 Application Examplesp. 8
23.6 Conclusionsp. 10
Referencesp. 10
24 Technical Considerations in the Construction of Vascular Anastomosesp. 1
24.1 Introductionp. 1
24.2 Materialsp. 2
24.3 Anastomosesp. 3
24.4 Surgical Applicationsp. 3
24.5 Patencyp. 6
Referencesp. 17
25 Minimally Invasive Cardiovascular Technologiesp. 1
25.1 Introductionp. 1
25.2 Angioplastyp. 2
25.3 Stentsp. 4
25.4 Aneurysm Treatmentp. 9
25.5 Embolic Filtersp. 11
25.6 Cardiac Ablation Cathetersp. 13
Referencesp. 13
26 Stereotactic Proceduresp. 1
26.1 Introductionp. 1
26.2 Methodsp. 1
26.3 Clinical Applicationsp. 3
26.4 Complicationsp. 5
26.5 New Directionsp. 5
26.6 Discussionp. 6
Referencesp. 6
VI Ambulatory Adaptations
27 Ambulatory Applications for Monitoring Physiological Parametersp. 1
27.1 Introductionp. 1
27.2 Systems Approach to Ambulatory Applicationsp. 3
27.3 Integrated Physiological Data Recordersp. 18
Referencesp. 22
Bibliographyp. 23
VII Recovery
28 Neural Prostheses for Movement Restorationp. 1
28.1 Introductionp. 1
28.2 Skeletal Muscles--Movement Actuatorsp. 2
28.3 Functional Electrical Stimulation Principlesp. 9
28.4 Instrumentation for FESp. 13
28.5 Neural Prostheses for Restoring Upper and Lower Extremity Functionsp. 29
Referencesp. 40
29 Pharmaceutical Technical Background on Delivery Methodsp. 1
29.1 Introductionp. 1
29.2 Central Nervous System: Drug Deliveryp. 2
29.3 Cardiovascular System: Drug Deliveryp. 4
29.4 Orthopedic: Drug Deliveryp. 6
29.5 Muscular System: Drug Deliveryp. 8
29.6 Sensory: Drug Deliveryp. 9
29.7 Digestive System: Drug Deliveryp. 10
29.8 Pulmonary: Drug Deliveryp. 11
29.9 Ear, Nose, and Throat: Drug Deliveryp. 13
29.10 Lymphatic System: Drug Deliveryp. 15
29.11 Reproductive System: Drug Deliveryp. 16
Referencesp. 17
VIII Alternative and Emerging Techniques
30 Hyperbaric Oxygen Therapyp. 1
30.1 Introductionp. 1
30.2 Indications and Outcomes for Hyperbaric Oxygen Treatmentp. 2
30.3 Summaryp. 8
Referencesp. 8
31 Image-Guided Thermal Therapyp. 1
31.1 Introductionp. 1
31.2 Thermal Therapyp. 2
31.3 Image-Guided Thermal Therapyp. 6
31.4 Delivery Strategies for Image-Guided Thermal Therapyp. 10
31.5 Conclusionsp. 20
Referencesp. 21
32 Medical Roboticsp. 1
32.1 Introductionp. 1
32.2 Robotic Reviewp. 1
32.3 Medical Robotics Historyp. 2
32.4 Clinical Applicationsp. 3
32.5 Technology Challenges/Research Areasp. 21
32.6 Conclusionsp. 24
Acknowledgmentsp. 24
Referencesp. 24
Indexp. 1