Cover image for Ellenberg and Rifkin's diabetes mellitus : theory and practice.
Ellenberg and Rifkin's diabetes mellitus : theory and practice.
Porte, Daniel.
Sixth edition / edited by Daniel Porte, Jr., Robert S. Sherwin, Alain Baron.
Publication Information:
New York : McGraw-Hill, Health Professions Division, [2003]

Physical Description:
xvii, 1047 pages : illustrations ; 28 cm
Subject Term:
Format :


Call Number
Material Type
Home Location
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RC660 .D542 2003 Adult Non-Fiction Non-Fiction Area-Reference

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A comprehensive reference on diabetes mellitus, covering basic biochemistry, physiology, and pathogenesis, as well as clinical diagnosis and treatment. The Sixth Edition includes five new chapters, plus new material on the genetic basis of the disease, new hypoglycemic drugs, mechanisms of hormone action, and regulation of hormone secretion.

Table of Contents

Gerald I. Shulman and Engene J. Barrett and Robert S. SherwinJ. Denis McGarry and Daniel W. FosterKevin Docherty and Donald F. SteinerBo Ahren and Gerald J. Taborsky, Jr.Jes K. Klarlund and Andrew D. Cherniack and Bruce R. Conway and Barbara VanRenterghem and Michael P. CzechDavid A. D'AlessioJohn M. Amatruda and James N. LivingstonMark L. Evans and Alan D. Cherrington and Mary Courtney Moore and Robert S. SherwinPeter J. Havel and Gerald J. Taborsky Jr.Stephen C. Woods and Randy J. Seeley and Denis G. Baskin and Michael W. SchwartzDaniel SteinbergDouglas E. VaughanMichael Brownlee and James N. LivingstonHindrik Mulder and Christopher B. NewgardCharles A. Janeway, Jr. and F. Susan WongEleazar ShafrirPer WestermarkSilvio E. InzucchiPeter H. Bennett and Marian J. Rewers and William C. KnowlerRamachandra G. Naik and Ake Lernmark and Jerry P. PalmerSteven E. Kahn and Daniel Porte, Jr.Jerrold M. Olefsky and Yolanta T. KruszynskaP. Antonio Tataranni and Clifton BogardusRobert V. Hogikyan and Jeffrey B. HalterOm P. Ganda and Eric S. BachmanAbhimanyu Garg and Joyce P. BarnettDavid H. Wasserman and Zhi-Qing Shi and Mladen VranicMichael R. DeFelippis and Bruce H. Frank and Ronald E. ChanceSuzanne M. Strowig and Philip RaskinDavid M. NathanPhilip E. Cryer and John E. GerichSundar Mudaliar and Robert R. HenryMargaret Grey and William V. TamborlaneElizabeth Delion Ennis and Robert A. KreisbergRobert MatzBrian P. Currie and Joan I. CaseyStephanie A. Amiel and K. George M.M. AlbertiBoyd E. Metzger and Richard L. Phelps and Sharon L. DooleyBernard L. Silverman and Edward S. Ogata and Boyd E. MetzgerElia J. Duh and Lloyd P. AielloRonald KleinMaria Luiza Avancini Caramori and Michael MauerRalph A. DeFronzoMartin J. Stevens and Irina Obrosova and Rodica Pop-Busui and Douglas A. Greene and Eva L. FeldmanEva L. Feldman and Martin J. Stevens and James W. Russell and Douglas A. GreeneAaron I. Vinik and Tomris Erbas and Michael A. Pfeifer and Eva L. Feldman and Martin J. Stevens and James W. RussellClay F. SemenkovichNorman M. KaplanLawrence H. Young and Deborah A. ChyunCameron M. Akbari and Frank W. LoGerfoWilliam C. ColemanFrancisco J. Baigorri and Jamie S. BarkinJohn E. OlerudJay S. SkylerDavid E.R. Sutherland and Rainer W.G. Gruessner and S. Michael Mauer and Angelika C. GruessnerGina R. Rayat and Ray V. Rajotte and Gregory S. KorbuttLester B. SalansPierre J. Lefevre and Andre J. ScheenChristopher D. Saudek and Shereen ArentElizabeth A. Walker and Judith Wylie-Rosett and Harry Shamoon
Contributorsp. ix
Prefacep. xvii
1. Integrated Fuel Metabolismp. 1
2. Ketogenesisp. 15
3. The Molecular and Cell Biology of the [beta] Cellp. 23
4. [beta]-Cell Function and Insulin Secretionp. 43
5. Mechanisms of Insulin Actionp. 67
6. Incretins: Glucose-Dependent Insulinotropic Polypeptide and Glucagon-Like Peptide 1p. 85
7. Glucagonp. 97
8. Role of the CNS in Glucose Regulationp. 117
9. Stress-Induced Activation of the Neuroendocrine System and Its Effects on Carbohydrate Metabolismp. 127
10. Food Intake and Energy Balancep. 151
11. Diabetes and Atherosclerosisp. 165
12. Endothelial Dysfunction and Vascular Thrombosis in Diabetesp. 175
13. Biochemical Mechanisms of Microvascular Diseasep. 181
14. Molecular Mechanisms and Genetic Engineering of Insulin-Secreting Cellsp. 197
15. Immunology Relevant to Diabetesp. 219
16. Diabetes in Animals: Contribution to the Understanding of Diabetes by Study of Its Etiopathology in Animal Modelsp. 231
17. Pathology of the Pancreas in Diabetes Mellitusp. 257
18. Classification and Diagnosis of Diabetes Mellitusp. 265
19. Epidemiology of Diabetes Mellitusp. 277
20. The Pathophysiology and Genetics of Type 1 (Insulin-Dependent) Diabetesp. 301
21. The Pathophysiology and Genetics of Type 2 Diabetes Mellitusp. 331
22. Insulin Resistancep. 367
23. Obesity and Diabetes Mellitusp. 401
24. Aging and Diabetesp. 415
25. Diabetes Secondary to Endocrinopathiesp. 425
26. Nutritional Management of the Person with Diabetesp. 437
27. Metabolic Implications of Exercise and Physical Fitness in Physiology and Diabetesp. 453
28. Insulin Chemistry and Pharmacokineticsp. 481
29. Intensive Management of Type 1 Diabetes Mellitusp. 501
30. Insulin Treatment of Type 2 Diabetes Mellitusp. 515
31. Hypoglycemia in Type 1 Diabetes Mellitus: The Interplay of Insulin Excess and Compromised Glucose Counterregulationp. 523
32. The Oral Antidiabetic Agentsp. 531
33. Behavioral and Family Aspects of the Treatment of Children and Adolescents with Type 1 Diabetesp. 565
34. Diabetic Ketoacidosisp. 573
35. Hyperglycemic Hyperosmolar Syndromep. 587
36. Host Defense and Infections in Diabetes Mellitusp. 601
37. Diabetes and Surgeryp. 611
38. The Mother in Pregnancies Complicated by Diabetes Mellitusp. 619
39. The Offspring of the Mother with Diabetesp. 641
40. Basic Pathobiology of the Eye and Its Complicationsp. 653
41. Retinopathy and Other Ocular Complications in Diabetesp. 663
42. Pathophysiology of Renal Complicationsp. 697
43. Diabetic Nephropathyp. 723
44. Pathogenesis of Diabetic Neuropathyp. 747
45. Somatosensory Neuropathyp. 771
46. Diabetic Autonomic Neuropathyp. 789
47. Diabetic Dyslipidemia: Pathophysiology and Treatmentp. 805
48. Hypertension and Diabetesp. 815
49. Heart Disease in Patients with Diabetesp. 823
50. Peripheral Vascular Disease in the Person with Diabetesp. 845
51. The Diabetic Footp. 859
52. Diabetes and the GI Systemp. 879
53. Diabetes and the Skinp. 895
54. Relationship of Glycemic Control to Diabetic Complicationsp. 909
55. Pancreas Transplantationp. 927
56. Islet Cell Transplantationp. 941
57. New Treatments for Diabetes Mellitus: Outlook for the Futurep. 949
58. Hypoglycemiap. 959
59. Economic Aspects: Insurance, Employment, and Licensingp. 973
60. Health Education for Diabetes Self-Managementp. 983
Indexp. 993