Cover image for AIDS update, 2002 : an annual overview of acquired immune deficiency syndrome
AIDS update, 2002 : an annual overview of acquired immune deficiency syndrome
Stine, Gerald James.
Personal Author:
Publication Information:
Upper Saddle River, N.J. ; London : Prentice Hall, [2002]

Physical Description:
xxiii, 502 pages ; 24 cm
Format :


Call Number
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RC607.A26 S753 2002 Adult Non-Fiction Central Closed Stacks

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For use in any course with significant coverage of AIDS, Virology, Immunology, Endocrinology, and Human Sexuality.

This text requires no biology prerequisite, and is the most comprehensive, authoritative, accurate, and up-to-date textbook on HIV/AIDS currently available as it is updated each and every year. It presents the entire 17-year chronology of the AIDS pandemic in a reasonable, logical, and scientific manner that interweaves biological, clinical, social, and legal discoveries in a uniquely readable presentation.

Table of Contents

1 Discovering AIDS, Naming the Disease
AIDS: A Disease or a Syndrome? What causes AIDS? How Does HIV Cause AIDS? Discovery of the AIDS Virus
The Centers for Disease Control and Prevention Reports
Defining the Illness: AIDS Surveillance
2 What Causes AIDS: Origins of the AIDS Virus
The Cause of AIDS: The Human Immunodeficiency Virus
Origin of HIV: The AIDS Virus
Summary on the Origin of HIV
3 Biological Characteristics of the AIDS Virus
Human Immunodeficiency Virus. (HIV)
Basic Genetic Structure of Retroviral Genomes
Genetic Mutation
Genetic Recombination in HIV
Distinct Genotypes (Subtypes/Clades) of HIV-1 Worldwide Based on ENV and GAG Proteins
4 Anti-HIV Therapy
Goals for Anti-HIV Therapy
Anti-HIV Drugs Having FDA Approval
FDA-Approved Nucleoside Analog Reverse Transcriptase Inhibitors
Development and Selection of HIV Drug-Resistance Mutants
How Combination Drug Therapy Can Reduce the Chance of HIV Drug-Resistance
Viral Load: It's Relationship to HIV Disease and AIDS
Use of Non-Nucleoside Analog Reverse Transcriptase Inhibitors
FDA-Approved Protease Inhibitors
Protease Inhibitors
2000 Two Most Sobering Reports on AIDS-Related Deaths
Pediatric Anti-HIV Therapy
Protease Inhibitors and Pregnancy
Some AIDS Therapy Information Hotlines
Other Organizations and Websites
5 The Immunology of HIV Disease/AIDS
The Immune System
Development of Human Immune System Cells
Human Lymphocytes: T Cells and B Cells
Antibodies and Viruses
Antibodies and HIV Disease
Fusin or CXCKR-4 (X4)
Genetic Resistance to HIV Infection
T4 Cell Depletion and Immune Suppression
Impact of T4 Cell Depletion
Role of Monocytes and Macrophages in HIV Infection
6 Opportunistic Infections and Cancers Associated with HIV Disease/AIDS
What Is an Opportunistic Disease? The Prevalence of Opportunistic Disease
Prophylaxis against Opportunistic Infections
Opportunistic Infections in HIV-Infected People
Cancer in AID Patients
Neuropathies in HIV Disease/AIDS Patients
7 A Profile of Biological Indicators for HIV Disease and Progression to AIDS
HIV Disease Defines
Stages of HIV Disease
HIV Disease without Symptoms, with Symptoms, and AIDS
Aspects of HIV Infection
Production of HIV-Specific Antibodies
Prognostic Biological Markers Related to AIDS Progression
HIV Infection of the Central Nervous System
Pediatric Clinical Signs and Symptoms
8 Epidemiology and Transmission of the Human Immunodeficiency Virus
HIV as a Communicable Disease
We Must Stop HIV Transmission Now! Epidemiology of HIV Infection
Transmission of Two Strains of HIV (HIV-1/HIV-2)
Is HIV Transmitted by Insects? Transmission of HIV
Casual Transmission
HIV Transmission in Family Household Settings
Noncasual Transmission
Public Confidence: Acceptance of Current Dogma on Routes of HIV Transmission
National AIDS Resources
9 Preventing the Transmission of HIV
The Millennium Virus
Global Prevention
Prevention of Infectious Diseases: HIV/AIDS
Preventing the Transmission of HIV
New Rules to an Old Game: Promoting Safer Sex
Injection Drug Use and HIV Transmission: The Twin Epidemics
HIV Prevention for Injection Drug Users
Prevention of Blood and Blood Product HIV Transmission
Infection Control Procedures
Partner Notification
HIV Vaccine Development
Vaccine Production
Problems in the Search for HIV Vaccine
Human HIV Vaccine Trials
10 Prevalence of HIV Infections, AIDS Cases, and Deaths among Select Groups in the United States
A Word about Data
The Millennium Year
2001 Old Formula for Estimating HIV Infections
Newer Formula for Estimating HIV Infections
Behavioral Risk Groups and Statistical Evaluation
Estimates of HIV Infection and Future AIDS Cases
United States Estimates Lead to Confusion
Whose Figures Are Correct? Issues of Credibility
Shape of the HIV Pandemic: United States
Estimates of Deaths and Years of Potential Life Lost Due to AIDS in the United States
Who Is Dying of AIDS? Life Expectancy
11 Prevalence of HIV Infection and AIDS Cases among Woman, Children, and Teenagers in the United States
Women and AIDS Worldwide
Women: HIV-Positive and AIDS Cases-United States
Pediatric HIV-Positive and AIDS Cases-United States
Global HIV Infections in Young Adults
Teenagers: HIV-Positive and AIDS Cases-United States
Other Useful Sources
12 Testing for Human Immunodeficiency Virus
Determining the Presence of Antibody Produced When HIV Is Present
Requests for HIV Testing
Reasons for HIV Testing
Immunodiagnostic Techniques for Detection Antibodies to HIV
Elisa HIV-Antibody Test
Western Blot Assay
Other Screening and Confirmatory Tests
Rapid HIV Testing
Viral Load: Measuring HIV RNA
Detection of HIV Infection in Newborns
FDA Approves Two Home HIV-Antibody Test Kits
Reporting HIV Infections
Who Should Be Tested for HIV Infection? Why Is HIV Test Information Necessary? Testing Competency, and Informed Consent
Person-to-Person: Disclosure of HIV Infection
13 AIDS and Society: Knowledge, Attitudes, and Behavior
The New Millennium and HIV/AIDS
HIV/AIDS Is an Unusual Disease
AIDS Is Here to Stay. AIDS
Blame Someone, Deja Vu
Fear: Panic and Hysteria over the Spread of HIV/AIDS in the United States
Actions of Course
Whom Is the General Public to Believe? AIDS Education and Behavior
The Character of Society
Federal Response to the HIV/AIDS Pandemic: Creation of an AIDS Industry
United States Government Believes HIV/AIDS Is a Threat to National Security
What a Difference a Decade Makes
Answers to Review Questions