Cover image for Conquering rheumatoid arthritis : the latest breakthroughs and treatments
Conquering rheumatoid arthritis : the latest breakthroughs and treatments
Lee, Thomas F.
Personal Author:
Publication Information:
Amherst, N.Y. : Prometheus Books, 2001.
Physical Description:
255 pages : illustrations ; 23 cm
General Note:
Includes index.
Format :


Call Number
Material Type
Home Location
Item Holds
RC933 .L43 2001 Adult Non-Fiction Non-Fiction Area
RC933 .L43 2001 Adult Non-Fiction Open Shelf
RC933 .L43 2001 Adult Non-Fiction Open Shelf

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As a biologist with more than thirty years of experience teaching a wide range of complex biomedical subjects and a person who suffers from rheumatoid arthritis (RA) himself, Dr. Thomas F. Lee is ideally suited to write a book that addresses the vital questions about the nature of the disease and the rationale behind its treatment. This is the only book that explains in layperson's terms the newest available therapies and the latest advances in our understanding of this often debilitating disease. These new insights have led to many molecular-based approaches already in clinical trial, and many more are waiting in the wings. All of these exciting developments are the result of the ongoing biotechnological revolution and a new understanding of the immune system aided by genetic research.
Over two million people in this country suffer from rheumatoid arthritis (RA), a debilitating autoimmune disease that ravages the delicate lining of the joints. As in other autoimmune diseases, instead of defending against foreign invaders, the immune system inexplicably attacks healthy tissue. RA causes systemic effects as well; not only are joints painful, through the destruction of bone and cartilage, but there is often accompanying fatigue, decreased appetite, depression, and muscle pain.
Dr. Lee not only supplies you with the latest facts on the discoveries about the disease, but he also provides numerous Web sites so that readers can follow this important story as it unfolds.

Author Notes

Thomas F. Lee (Goffstown, NH) is professor of microbiology and biotechnology at St. Anselm College and the author of the critically acclaimed The Human Genome Project: Cracking the Genetic Code of Life and Gene Future: The Promise and Perils of the New Biology.

Reviews 1

Library Journal Review

The cause and treatment of many diseases is being advanced on a molecular level, an area of science and medicine not easily understood by the average person. Lee (microbiology and biotechnology, St. Anselm Coll.; The Human Genome Project) here attempts to make sense of recent research in rheumatoid arthritis (RA), focusing on the evolution of molecular and gene-based therapies for this autoimmune disease, which affects two million adults and children in the United States. Lee offers detailed scientific explanations of RA, an overview of the immune system and its role in the disease, and a description of the inflammatory sequence that launches RA. He then discusses the multibillion-dollar research efforts by universities, biotechnology centers, and the pharmaceutical industry to develop gene-based therapies and follows up with a discussion of the nature of clinical trials and a survey of therapies currently in the pharmaceutical pipeline. Lee mentions the ethical implications of human genome research but admits that it is not the intent of his book to discuss this area of debate thoroughly. Recommended for consumer health collections. Lisa L. McCormick, Jewish Hosp. Health Sciences Lib., Cincinnati (c) Copyright 2010. Library Journals LLC, a wholly owned subsidiary of Media Source, Inc. No redistribution permitted.