Cover image for Childhood cancer : a handbook from St. Jude Children's Research Hospital with contributions from St. Jude clinicians and scientists
Childhood cancer : a handbook from St. Jude Children's Research Hospital with contributions from St. Jude clinicians and scientists
Steen, R. Grant.
Publication Information:
Cambridge, Mass. : Perseus Pub., [2000]

Physical Description:
xvi, 606 pages : illustrations ; 25 cm
Reading Level:
1360 Lexile.
Subject Term:
Format :


Call Number
Material Type
Home Location
Item Holds
RC281.C4 C45 2000 Adult Non-Fiction Central Closed Stacks
RC281.C4 C45 2000 Adult Non-Fiction Open Shelf

On Order



Approximately 20,000 new cases of childhood cancer are diagnosed each year. Until now, the families who receive this devastating news have had no one volume to turn to for up-to-date information, clear answers, and authoritative resource recommendations. To meet this need, clinicians and scientists at the world-famous St. Jude Children's Research Hospital have compiled the most comprehensive and compassionate family reference available. From practical matters, such as what tests to expect during diagnosis, treatment options for each kind of cancer, and the value and availability of clinical trials, to the emotional needs of children battling cancer and coping with life afterward, this invaluable guide will offer immeasurable comfort to parents and patients facing the family crisis of childhood cancer.Founded in 1962 by the late entertainer Danny Thomas, St. Jude Children's Research Hospital in Memphis, Tennessee, has treated more than 15,000 children from across the United States and more than sixty foreign countries. It is the first institution established for the sole purpose of conducting basic and clinical research into catastrophic childhood diseases, and is the largest childhood cancer research center in the United States.

Author Notes

Dr. R. Grant Steen is currently studying brain cancer at the St. Judge Children's Research Hospital in Memphis, Tennessee. He is an expert in tumor physiology and tumor cell biology, and his research interest is the metabolic imaging of cancer. He employs magnetic resonance imaging (MRI) to estimate tumor perfusion, in an effort to predict tumor drug delivery. He received his doctorate from the University of California at Los Angeles, and he was furthur trained in research at the California Institute of Technology and the Johns Hopkins University School of Medicine. He taught at the University of Washington, where he was an Assistant Professor of Radiology and of Bioengineering, and he has written more than 25 papers which appeared in scientific journals.

Reviews 3

Booklist Review

The 50 chapters of this handbook deal clearly and thoroughly with many aspects of childhood cancer. Their authors point out the differences between cancer in children and in adults and emphasize the major, often remarkable improvements in diagnosis, treatment, and survival rate during the past few decades. Chapters describing types of cancer, tests, equipment, and techniques are interspersed with chapters on such topics as what to ask the doctor, management of pain, psychosocial and spiritual support, and insurance matters. Designed so that the reader can learn, first, about general medical and surgical topics and then about specific types of cancer, as needed, the book frowns upon alternative therapies but does consider complementary medicine approaches. Many tables aid in organizing material and reinforcing a vast amount of information. The book concludes by listing sources of additional information and support; a glossary would have been another nice addition. --William Beatty

Library Journal Review

Making informed medical decisions for a child with cancer is difficult, but this textDa cutting-edge textbook on pediatric cancer written expressly for lay readers by St. Jude's clinicians and scientistsDprovides compassionate advice and information that should help ease the process. (Founded in 1962 by entertainer Danny Thomas, St. Jude Children's Research Hospital is today recognized as a leader in children's diseases and, specifically, in children's cancer.) This one-volume resource is outstanding in every wayDorganization, content, authority, scope, and special features. Organized around seven broad sections for the comprehensive coverage of key issues (basics, diagnosis, treatment, patient care, cancer types, and recovery), the 56 chapters are each authored by a specialist in the field. The writing is intelligent and clear but never patronizing. Information on hard-to-find topics such as the late effects of cancer treatments (e.g., adverse effects that may show up years later) and an excellent introduction to the genetics of cancer is included. A first-rate list of information resources as well as a chapter on how to find reliable web-based information (authored by a medical librarian) are added bonuses. An exceptional contribution to cancer patient information, this is essential for all consumer health collections.DGail Hendler, Memorial Sloan-Kettering Cancer Ctr., New York (c) Copyright 2010. Library Journals LLC, a wholly owned subsidiary of Media Source, Inc. No redistribution permitted.

Choice Review

Sixty professional staff members assembled this compilation of information on pediatric cancer. Ostensibly written for "anyone" close to a child diagnosed with cancer, it contains some chapters written in such technical language that even the most determined parents may become discouraged. Almost all patients at St. Jude are enrolled in clinical trials. It is paramount that parents understand safeguards for human subjects and research protocols. Parents will also benefit from chapters on alternative and complementary therapies, as well as reliable Web sites and chat rooms. Chapters of middle-range technicality cover diagnoses, treatments, care, and possible aftermath of treatments. Most technical are chapters on specific types of cancers. Helpful for both parents and clinicians are chapters on treatment side effects, infection control, nutrition, pain reduction, and follow-up care. The chapters clearly written for parents and patients cover survivors' quality of life issues, coping, grief, and social adjustment. Important practical concerns including health insurance, educational services, and civil rights under US statutes are also addressed. Judicious regrouping of chapters or division of the material into two books might improve the usefulness of this welcome but prodigious effort. All levels. M. K. Snooks; University of Houston--Clear Lake

Table of Contents

Contributorsp. vii
Prefacep. xiii
Acknowledgmentsp. xv
Part 1 Overview of Childhood Cancerp. 1
1 What is Cancer?p. 3
2 How Common is Childhood Cancer?p. 11
3 A Historical Perspective on Childhood Cancerp. 19
4 The Biology of Childhood Cancerp. 35
The Genetics of Childhood Cancerp. 47
Part 2 How Cancer is Diagnosedp. 59
6 The Patient History and Physical Examinationp. 61
7 Laboratory Testsp. 71
8 Diagnostic Imagingp. 79
9 Tumor Biopsyp. 91
10 Tumor Pathologyp. 95
11 What to Ask Your Doctorp. 103
Part 3 How Cancer is Treatedp. 109
12 Treatment Optionsp. 111
13 Surgeryp. 119
14 Radiation Therapyp. 127
15 Chemotherapyp. 141
16 Bone Marrow Transplantationp. 155
17 Immune Therapyp. 167
18 Medical Research in Childrenp. 175
19 The Importance of Clinical Trialsp. 183
20 Alternative and Complementary Therapiesp. 195
21 Future Directions in Cancer Treatmentp. 205
Part 4 How the Patient is Cared Forp. 213
22 Patient Care from the Patient's Perspectivep. 215
23 Managing Early Treatment Side Effectsp. 221
24 Reducing Painp. 229
25 Nutrition for the Cancer Patientp. 243
26 Controlling Opportunistic Infectionsp. 255
27 Blood and Plasma Transfusionsp. 263
28 Psychosocial Support for the Child with Cancerp. 271
29 Spiritual Support for Children and Familiesp. 283
30 Coping with Tumor Recurrencep. 293
31 When Cancer is Terminalp. 305
Part 5 The Leukemias and Lymphomasp. 311
32 Acute Lymphoblastic Leukemiap. 313
33 Acute Myelogenous Leukemiap. 327
34 Hodgkin's Diseasep. 337
35 Non-Hodgkin's Lymphomap. 345
Part 6 The Solid Tumorsp. 353
36 Retinoblastomap. 355
37 Brain Tumorsp. 363
38 The Ewing's Sarcoma Family of Tumorsp. 383
39 Wilms Tumorp. 391
40 Neuroblastomap. 401
41 Liver Cancerp. 409
42 Osteosarcomap. 415
43 Rhabdomyosarcomap. 425
44 The Infrequent Childhood Cancersp. 433
Part 7 Recovery from Cancerp. 445
45 The Physicalm Aftermath of Cancerp. 447
46 The Psychosocial Impact of Cancerp. 461
47 Social Concerns of Children with Cancerp. 471
48 Educational Concerns for Children with Cancerp. 477
49 Late Effects of Cancer Therapyp. 491
50 Long-Term Follow-Up After Childhood Cancerp. 505
51 Reducing Exposure to Cancer Risk Factorsp. 517
53 Insurance and Financial Issues Associated with Cancerp. 550
54 Grieving and Emotional Recoveryp. 551
55 Locating and Evaluating Medical Information on the World Wide Webp. 561
56 Afterwords: an Epiloguep. 569
Appendix 1 Web Sites for Medical Informationp. 575
Appendix 2 Educational and Support Resources for Cancer Patients and Their Parentsp. 579
Notes and Sourcesp. 581
Indexp. 595