Cover image for Human embryology & developmental biology
Human embryology & developmental biology
Carlson, Bruce M.
Personal Author:
Second edition.
Publication Information:
St. Louis : Mosby, [1999]

Physical Description:
xvii, 494 pages : illustrations (some color) ; 28 cm
Format :


Call Number
Material Type
Home Location
Item Holds
QM601 .C29 1999 Adult Non-Fiction Central Closed Stacks-Oversize

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For the latest information about embryological development, turn to HUMAN EMBRYOLOGY AND DEVELOPMENTAL BIOLOGY. This comprehensive, clearly written textbook emphasizes the molecular basis of human embryological development, explaining the "why" in addition to the "how." Many full-color clinical photographs and illustrations stress the function of embryological structures and the progression of development. All information has been updated to include the most current research findings and contemporary clinical applications. Chapter summaries and review questions aid in students' learning. This edition includes new clinical photographs, Clinical Correlation boxes, and clinical vignettes.

Discusses development in terms of activity at the molecular and cellular level to explain embryological development, instead of just describing structure and function. Includes over 300 color drawings in striking detail, drawn in accordance with the universally-accepted embryological color code for more realistic representation. Contains end-of-chapter questions to provide quick review of the most important concepts for better comprehension. Features chapter summaries of the key concepts to reinforce comprehension and encourage student self-assessment. Uses boldface key terms to emphasize the terms and concepts that students most need to know. Features a clear, concise, understandable narrative that focuses on the progression of development to provide easy comprehension of difficult and complex material. Provides many full color photographs of clinical conditions.

Spanish version also available, ISBN: 84-8174-471-9

Author Notes

Bruce M. Carlson, MD, PhD: University of Michigan

Table of Contents

Developmental Tables
Carnegie Stages of Early Human Embryonic Development (Weeks 1-8)p. xiii
Major Developmental Events During the Fetal Periodp. xiv
Part I Early Development and the Fetal-Maternal Relationship
Chapter 1 Getting Ready for Pregnancyp. 3
Gametogenesisp. 3
Preparation of the Female Reproductive Tract For Pregnancyp. 16
Reproductive Target Tissuesp. 20
Chapter 2 Transport of Gametes and Fertilizationp. 27
Ovulation and Egg and Sperm Transportp. 27
Fertilizationp. 32
Chapter 3 Cleavage and Implantationp. 43
Cleavagep. 43
Embryo Transport and Implantationp. 53
Chapter 4 Molecular Basis for Embryonic Developmentp. 65
Fundamental Molecular Processes in Developmentp. 65
Chapter 5 Formation of Germ Layers and Early Derivativesp. 83
Two-Germ-Layer Stagep. 83
Gastrulation and the Three Embryonic Germ Layersp. 85
Induction of the Nervous Systemp. 89
Cell Adhesion Moleculesp. 97
Chapter 6 Establishment of the Basic Embryonic Body Planp. 103
Development of the Ectodermal Germ Layerp. 103
Development of the Mesodermal Germ Layerp. 108
Development of the Endodermal Germ Layerp. 118
Basic Structure of 4-Week Old Embryop. 122
Chapter 7 Placenta and Extraembryonic Membranesp. 129
Extraembryonic Tissuesp. 129
Chorion and Placentap. 132
Placenta After Birthp. 143
Placenta and Membranes in Multiple Pregnanciesp. 143
Chapter 8 Developmental Disorders: Causes, Mechanisms, and Patternsp. 151
General Principlesp. 152
Causes of Malformationsp. 155
Developmental Disturbances Resulting in Malformationsp. 164
Part II Development of the Body Systems
Chapter 9 Integumentary, Skeletal and Muscular Systemsp. 173
Integumentary Systemp. 173
Skeletonp. 183
Muscular Systemp. 193
Chapter 10 Limb Developmentp. 209
Initiation of Limb Developmentp. 209
Regulative Properties and Axial Determinationp. 210
Outgrowth of Limb Budp. 211
Zone of Polarizing Activity and Morphogenetic Signalingp. 215
Development of Limb Tissuesp. 222
Chapter 11 Nervous Systemp. 233
Establishment of Nervous Systemp. 233
Early Shaping of Nervous Systemp. 234
Histogenesis Within the Central Nervous Systemp. 234
Craniocaudal Pattern Formation and Segmentationp. 240
Peripheral Nervous Systemp. 245
Autonomic Nervous Systemp. 249
Later Structural Changes in the Central Nervous Systemp. 252
Ventricles, Meninges, and Cerebrospinal Fluid Formationp. 264
Cranial Nervesp. 265
Development of Neural Functionp. 267
Chapter 12 Neural Crestp. 277
Origins of Neural Crestp. 277
Migrations of Neural Crestp. 278
Differentiation of Neural Crest Cellsp. 278
Major Divisions of Neural Crestp. 280
Chapter 13 Sense Organsp. 291
Eyep. 292
Earp. 306
Chapter 14 Head and Neckp. 317
Early Development of Head and Neckp. 317
Fundamental Organization of Pharyngeal Regionp. 319
Development of Facial Regionp. 321
Development of Pharynx and Its Derivativesp. 335
Chapter 15 Digestive and Respiratory Systems and Body Cavitiesp. 353
Digestive Systemp. 353
Respiratory Systemp. 374
Body Cavitiesp. 379
Chapter 16 Urogenital Systemp. 393
Urinary Systemp. 393
Genital Systemp. 401
Sexual Duct Systemp. 412
External Genitaliap. 419
Chapter 17 Cardiovascular Systemp. 429
Developmental of Vascular Systemp. 429
Developmental and Partitioning of Heartp. 446
Initiation of Cardiac Functionp. 455
Fetal Circulationp. 456
Chapter 18 Fetal Period and Birthp. 477
Growth and Form of Fetusp. 477
Fetal Physiologyp. 477
Parturitionp. 492
Adaptations to Postnatal Lifep. 494
Overviewp. 496
Answers to Clinical Vignettes and Review Questionsp. 499
Indexp. 507