Cover image for Encyclopedia of human biology
Encyclopedia of human biology
Dulbecco, Renato, 1914-2012.
Second edition.
Publication Information:
San Diego : Academic Press, [1997]

Physical Description:
9 volumes : illustrations (some color) ; 29 cm
v. 1. A-Bi -- v. 2. Bi-Com -- v. 3. Con-Fe -- v. 4. Fl-Im -- v. 5. In-Mu -- v. 6. My-Pl -- v. 7. Po-Se -- v. 8. Si-Z -- v. 9. Index.









Format :


Call Number
Material Type
Home Location
Item Holds
QP11 .E53 1997 V.8 Adult Non-Fiction Non-Fiction Area-Oversize
QP11 .E53 1997 V.7 Adult Non-Fiction Non-Fiction Area-Oversize
QP11 .E53 1997 V.6 Adult Non-Fiction Non-Fiction Area-Oversize
QP11 .E53 1997 V.1 Adult Non-Fiction Non-Fiction Area-Oversize
QP11 .E53 1997 V.2 Adult Non-Fiction Non-Fiction Area-Oversize
QP11 .E53 1997 V.4 Adult Non-Fiction Non-Fiction Area-Oversize
QP11 .E53 1997 V.9 Adult Non-Fiction Non-Fiction Area-Oversize
QP11 .E53 1997 V.5 Adult Non-Fiction Non-Fiction Area-Oversize
QP11 .E53 1997 V.3 Adult Non-Fiction Non-Fiction Area-Oversize

On Order



The Encyclopedia of Human Biology, Second Edition provides complete coverage of the vast subject area of human biology--no other reference work available offers such a detailed and comprehensive treatment of the subject. Including more than 670 articles in 37 different biological fields, this fully revised edition features one of the most renowned editorial Advisory Boards ever assembled. The Second Edition offers more than 75% new, updated, and revised content including approximately 150 new articles. In keeping with the first editions high standards, all articles have been subjected to rigorous peer review to ensure consistent presentation of the highest quality. Unlike other encyclopedias which use numerous fragmented entries to treat a subject, the Encyclopedia examines each subject in individual, cohesive articles. Arranged alphabetically for easy access, each article--about ten pages in length-contains a brief outline, glossary of unusual terms, a short concise definition of the subject, an in-depth development of the topic, recent bibliography, extensive cross references to other articles in the Encyclopedia, and tables and illustrations including more than 100 color plates.

The Encyclopedia of Human Biology is already an important part of the collection of more than 2000 reference libraries. This Second Edition provides even greater value to the reader with its enlarged scope and updated content. It offers: Practicing scientists in all settings an up-to-date, authoritative, and reliable resource for preparing grant proposals, research papers, and background information on important, wide-ranging biological topics; College preparatory, undergraduate, and graduate students a one-stop source that will assist them with their course work, term papers, and dissertations; Researchers working in peripheral areas a concise explanation of the key issues and background reading suggestions in a given area; Educated general readers a broad spectrum of accurate, current information on all aspects of human biology.

Author Notes

Dr. Renato Dulbecco is President Emeritus and Distinguished Resident Professor at the Salk Institute for Biological Studies in La Jolla, California. Known for his pioneering work in cancer-causing viruses, Dulbecco was awarded the Nobel Prize in medicine/physiology in 1975. At the beginning of his career, Dulbecco devoted his work to the study of virology. During his early research, he developed what continues to be the most widely used technique for growing and maintaining cells in culture and for measuring the activity of animal viruses, such as poliovirus. Subsequently, Dulbecco, working with cancer-producing viruses, was able to show how genes of the virus interact with those of the host cell in tissue culture, which was a fundamental discovery in understanding the uncontrolled proliferation of cells in the cancer process. Dulbecco was born and educated in Italy, and he received his doctorate of medicine from the University Turin in 1936. He joined the Salk Institute as one of the original group of Fellows in 1963 and was associated with the Institute until 1972. From 1972 through 1977, Dulbecco was Deputy Director of the Imperial Cancer Research Laboratory in London. Since rejoining the Salk Institute in 1977, he has held the position of Distinguished Research Professor and Senior Clayton Foundation Investigator. In 1988 he was named President of the Salk Institute. Dulbecco's more recent research has involved the study of the origin of breast cancer. He has studied the various cell types that comprise breast tissue, a necessary first step in the process of understanding how some cells undergo transformation and become malignant. Dulbecco has used monoclonal antibody techniques to study breast cancer in laboratory animals and in humans, with the objective of developing new and reliable means of classifying cells in the breast, and identifying those that may be susceptible to carcinogenic agents. Some of the antibodies he produced have been studied for clinical

Reviews 2

Library Journal Review

With its clear organization, comprehensive and thorough coverage, reliable and coherent information, and easy-to-access format, this eight-volume reference on human biology is a unique and valuable addition to the scientific literature. Designed as a review of current knowledge in the field covering specialized subjects such as biochemistry, cytology, genetics, and immunology, this well-written work is edited by Dulbecco, a Nobel laureate and president of the Salk Institute, along with an impressive advisory board. The 620 articles, each about ten pages in length, are written by recognized experts in their fields in authoritative but easy-to-understand language and are alphabetically arranged by topic. Each entry contains a brief outline, a glossary of unusual terms, a definition and an in-depth development of the subject, a recent bibliography, along with cross references, illustrations, and tables. Intended for a wide audience of scientists, researchers, undergraduate and graduate students, and even general readers with a background in science, this outstanding tool is highly recommended for all libraries, especially for those whose need for scientific sources can justify the cost.-- Marilyn Rosenthal, Nassau Community Coll. Lib., Garden City, N.Y. (c) Copyright 2010. Library Journals LLC, a wholly owned subsidiary of Media Source, Inc. No redistribution permitted.

Choice Review

This imposing set covers all aspects of its subject, from molecular biology to sociobiology, including medicine and psychology. It consists of long signed articles by well-known senior academic authorities on broad topics, varying in length from five to 20 pages. It is greatly expanded from the first edition (CH, Oct'91); about one-third of the articles are entirely new, while the others are divided equally between those significantly rewritten, those slightly modified, and those totally unchanged. The articles are arranged alphabetically but without consistent pattern (e.g., "Antibacterial drugs" but "Chemotherapy. Antiviral agents"). Controversial subjects are treated in several partly overlapping articles; e.g., both "Schizophrenic disorders" (with a strong biological slant) and "Schizophrenia, Psychosocial Treatment." Many topics are covered in several overlapping articles, or at several different levels of specificity; for example, there is a nine-page article "Brain," but also articles of similar length titled "Brain, Central Gray Area," "Cortex," and "Neocortex." Unexpectedly, there are no individual articles on the cerebellum or the medulla. For access to specific concepts, it is necessary to use the appropriate but not visually prominent cross-references, and the good but not very detailed index in v. 9. The level of presentation varies. The preface states that "only a general knowledge of biology is expected," which may be true for the medical topics, less so for the molecular or physiological ones. Black-and-white drawings, inadequate in number, sometimes marginal in quality, and often insufficiently detailed are dispersed throughout. A small section of eight to ten pages of color illustrations (also often insufficiently detailed, especially for anatomy) is located very inconveniently in the center of each volume. There are occasional tables and graphs. In general, the presentations rely much more heavily on text than on illustrations, which is inappropriate for almost all the subjects. Biology is inherently visual, and modern publications, from elementary texts to scholarly journals, make extensive use of color to clarify complex relationships. The text of many articles is written in rather general terms, not always giving appropriate specific examples. In the biochemical chapters, chemical formulas are frequently avoided; in the medical chapters, the options are drastically oversimplified; in the population-based chapters, actual numerical data--and especially time series--are rarely shown. Most of the physiological chapters make extensive and appropriate use of diagrams and of chemical and mathematical formulas, although even here the diagrams often have the rough-and-ready style of class handouts. Many of the articles give only a few general references, without citations to what data or illustrations they present. Frequently the most important workers in the field are mentioned by name in the text, but without citations to their specific works. In many articles, references have been updated through 1995, which is perhaps all that can be expected. Some articles, however, primarily list outdated elementary textbooks with sometimes one more recent textbook by way of updating, and a few articles list only works by the author of the article or his/her research group. Some details typify the obsolete editorial approach: medical articles illustrated with recognizable full-face illustrations of patients; illustrations showing attractive figures in provocative positions to illustrate nonsexual subjects; articles implying a condescending attitude toward Third World peoples; many articles concluding with puerile verbiage such as "the active research along these lines suggest [sic] that some treatment ... will eventually be found." Several articles illustrate the variations found. The article "Mitochondria" has 12 pages of text with only four illustrations, seven references (all review articles or books), and mentions dozens of specific syndromes and genes but gives no specific citations. "Serotonin in the Central Nervous System" has seven pages of text with no chemical formulas or drawings whatsoever and references to eight articles, seven of them reviews. "Bioethics," not revised since the first edition, is written in exceptionally general terms and has references to only five books from the 1980s and one from 1993; the set contains no other article in this entire field. On the other hand, "DNA Repair" has eight pages, about half of which consist of illustrations, with citations to three review articles and three key recent primary research articles. The paucity of references and specifics presumably stems from a desire to avoid challenging readers, but the only justification for the skimpy illustrations would be cost savings: but consider the price of this set. A better source for this material would be a well-chosen collection of recent textbooks. In spite of key deficiencies in presentation, the wide coverage recommends this work--reluctantly--to undergraduate libraries. Teachers in areas covered by it would do well to familiarize themselves with the relevant articles, since they will certainly see much of the text again in student papers. D. Goodman Princeton University

Table of Contents

Preface to the First Edition
Preface to the Second Edition
A Guide to Using the Encyclopedia
Volume 1 - A-Bi: Abortion, Spontaneous
Acquired Immune Deficiency Syndrome, Epidemic
Acquired Immune Deficiency Syndrome, Infectious Complications
Acquired Immune Deficiency Syndrome, T-Cell Subsets
Acquired Immune Deficiency Syndrome, Virology
Acute Phase Response
Adaptational Physiology
Adaptation and Human Geographic Variation
Adenosine Triphosphate (ATP)
Adipose Cell
Adrenal Gland
Adrenergic and Related G Protein-Coupled Receptors
Affective Disorders, Genetic Markers
Affective Responses
Aging and Language
Aging, Molecular Aspects
Aging, Psychiatric Aspects
Alcohol, Impact on Health
Alcohol Toxicology
Alkaloids in Medicine
Alzheimer's Disease
Amoebiasis, Infection with Entamoeba histolytica
Amyotrophic Lateral Sclerosis
Anaerobic Infections in Humans
Animal Models of Disease
Animal Parasites
Antibiotic Inhibitors of Bacterial Cell Wall Biosynthesis
Antibody-Antigen Complexes: Biological Consequences
Antibody Diversity (Clonal Selection)
Anti-Inflammatory Steroid Action
Antimicrobial Agents, Impact on Newborn Infants
Antimicrobial Drugs
Antinuclear Antibodies and Autoimmunity
Antisense Inhibitors
Articular Cartilage and the Intervertebral Disc
Articulations, Joints
Artificial Cells
Artificial Heart
Artificial Kidney
Artificial Skin
Ascorbic Acid
Ataxia-Telangiectasia and the ATM Gene
Atherosclerosis: From Risk Factors to Regulatory Molecules
ATP Synthesis in Mitochondria
Atrial Natriuretic Factor
Attitudes as Determinants of Food Consumption
Attraction and Interpersonal Relationships
Autoimmune Disease
Autonomic Nervous System
Bacterial Infections, Detection
B-Cell Activation
Behavioral Development, Birth to Adolescence
Behavioral Effects of Observing Violence
Behavior: Cooperative, Competitive, and Individualistic
Behavior Measurement in Psychobiological Research
Bile Acids
Binocular Vision and Space Perception
Bioenergetics and the Adrenal Medulla
Biomineralization and Calcification
Birth Control
Birth Defects
Volume 2 - Bl-Co: Blood Binding of Drugs
Blood-Brain Barrier
Blood Coagulation, Hemostasis
Blood Coagulation, Tissue Factor
Blood Platelets and Their Receptors
Blood Sampling, Fetal
Blood Supply Testing for Infectious Diseases
Body Fat, Menarche, and Fertility
Body Temperature and Its Regulation
Bone Cell Genes, Molecular Analysis
Bone Density and Fragility, Age-Related Changes
Bone, Embryonic Development
Bone Marrow Transplantation
Bone Regulatory Factors
Bone Remodeling
Bone Tumors
Bony Pelvis of Archaic Homo sapiens
Brain, Central Gray Area
Brain Evolution
Brain, Higher Function
Brain Messengers and the Pituitary Gland
Brain Regulation of Gastrointestinal Function
Brain Spectrin
Brain Tumors
Breast Cancer Biology
Calcium Antagonists
Calcium, Biochemistry
Cancer Genetics
Cancer Immunology
Cancer Prevention
Cardiac Muscle
Cardiogenic Reflexes
Cardiovascular Hormones
Cardiovascular Responses to Weightlessness
Cardiovascular System, Anatomy
Cardiovascular System, Pharmacology
Cardiovascular System, Physiology and Biochemistry
Catecholamines and Behavior
CD8 and CD4: Structure, Function, and Molecular Biology